In these cases, Down's syndrome is not related to age of mother, but runs in the family of either father or mother. symptoms-short stature weal muscles small, low-set ears irregular mouth and tongue cognitive disabilities heart defects prone to health problems. Cri du chat. influence: Deletion - chromosome 5 is missing an end piece symptoms: Cri du chat syndrome is a chromosomal condition that affects the development of the brain and the face of the infant. it causes a high pitched cry, intellectual disability, microcephaly, hypotonia, and facial features like a cat's face. learn more about the symptoms, causes, genetics, and inheritance of this condition from medlineplus genetics. Symptoms Symptoms include: Cry that is high-pitched and may sound like a cat Downward slant to the eyes Epicanthal folds, an extra fold of skin over the inner corner of the eye Low birth weight and slow growth Low-set or abnormally shaped ears Hearing loss Heart defects Intellectual disability Partial webbing or fusing of fingers or toes Symptoms of Williams syndrome include: Chronic ear infections and/or hearing loss. Dental abnormalities, such as poor enamel and small or missing teeth. Elevated calcium level in the blood. Endocrine abnormalities: hypothyroidism, early puberty and diabetes in adulthood. Farsightedness. Feeding difficulties in infancy. Cri-du-chat ( cat cry; MIM #123450) is a deletion syndrome, with an incidence of approximately 1 in 45,000 liveborn …. Chromosomal translocations, deletions, and inversions. …region is likely to lead to phenotypic manifestations. Perhaps the most well-known example is Cri-du-chat syndrome, which is due to a terminal deletion of the short Other symptoms of cri du chat may include: Low birth weight. Delayed growth. Feeding difficulties, such as poor sucking, difficulty swallowing ( dysphagia) and GERD. Weak muscle tone ( hypotonia ). Curvature of the spine ( scoliosis ). Heart defects. Developmental delays, such as head control, .

symptoms of cri du chat